Conference Summary

The Acute Kidney Injury Science Research Conference (SRC) is a 3.5-day, integrated bench to bedside conference open to the entire AKI research community focusing on topical aspects of current research and approaches in both the basic and clinical science of acute kidney injury. Attendees and invited speakers will include established investigators and trainees from academia, industry, and government agencies involved in different aspects of AKI research, with approximately equal numbers involved in clinical and basic sciences AKI research. We expect about half of the attendees will be trainees, while the remainder will be established investigators and scientists from academia, industry, and government. This meeting will provide young investigators and trainees access to leaders in the field. Networking and camaraderie among AKI investigators from academic, industry, and government backgrounds will be promoted.

Themes of the conference include: 1) understanding the cellular and molecular mechanisms involved in tissue injury, repair, and fibrosis after AKI, and the impact of co-morbidities, such as diabetes and old age, on these responses; 2) new approaches to optimize tissue acquisition, interrogation, and data integration by the Kidney Precision Medicine Program, to provide a state-of-the-art overview of the cellular and molecular heterogeneity of human AKI from human tissue interrogation studies, and to discuss how these new findings will enable us to differentiate sub-types of human AKI and might impact the development of new approaches to study mechanisms and treatment of AKI; and 3) a forum to discuss the challenges facing investigators and new approaches that are being used to optimize drug development for AKI, including the pros and cons of target-based and phenotyping drug screening, state-of-the-art pre-clinical models for drug discovery in human disease, clinical phenotyping of human AKI (including the use of biomarkers), and new approaches used for AKI clinical study design. It is anticipated that proceedings from the conference will be published in Seminar in Nephrology in early 2020.

Conference session topics will include:

  • Mechanisms injury
  • Organ interactions in AKI
  • Clinical studies in human AKI
  • Mechanisms of repair
  • Mechanisms of maladaptive repair and fibrosis
  • Human tissue interrogation in AKI
  • Immunological mechanisms of injury and repair
  • Challenges of drug development for AKI

In addition to an opening keynote lecture from Claudio Ronco, MD (International Research Institute in Vincenza, Italy), there will be state-of-the-art clinical and basic science lectures on acute kidney injury. The conference will feature 11 oral sessions, two poster sessions, and two evening receptions. Four career development sessions will include a career discussion panel, a small group career discussion session, and two one-on-one “Meet the Expert” lunches.


Important Dates

  • Advance registration deadline Wednesday, June 5, 2019
  • Last day to register Saturday, June 29, 2019

Conference Location

Asilomar Conference Grounds
800 Asilomar Avenue
Pacific Grove, CA 93950 USA

Conference Organizers

Mark de Caestecker, MB, BS, PhD
Physician Scientist, Nephrologist, and Professor of Medicine,Vanderbilt University Medical Center, USA

Ray Harris, MD
Physician Scientist, Nephrologist, and Professor of Medicine Vanderbilt University Medical Center, USA

Neil Hukriede, PhD
Bench Scientist, Professor, and Vice Chair, Department of Developmental Biology University of Pittsburgh, USA

Edward Siew, MD, MSCI
Clinical Scientist, Nephrologist, and Associate Professor, Vanderbilt University Medical Center, USA

Keynote Speaker

Claudio Ronco, MD
The International Research Institute, Vincenza, Italy

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