Conference Summary

This FASEB Science Research Conference (SRC) is one of the longest-running meetings in the FASEB SRC series, originally launched in the early 1990s in recognition of the cloning and characterization of major glucose transporter isoforms. Over the ensuing years, the meeting has evolved to embrace emergent topics in metabolic control mechanisms related to obesity, diabetes, cardiovascular disease, and cancer. The meeting has consistently attracted major leaders in these fields, with representation of promising young scientists. Recent progress in this area of research has been explosive, and the meeting will highlight several paradigm-shifting discoveries derived from the application of new “big-data” technologies.

This year’s conference will include a lively mix of investigators studying glucose transporter biology and metabolic regulation, including researchers applying “fluxomics” and systems biology methods to advance our understanding of metabolic health. We have invited approximately 40 scientists from institutions and companies worldwide to speak, and an additional dozen prominent scientists to serve as session chairs and discussion leaders. In addition to these speakers, we will be selecting short talks from abstracts to be presented by junior trainees. We will also run several poster sessions and, continuing a new and very well-received event launched at the 2013 meeting, conduct a two-hour “open mike” session for volunteers to present recent discoveries for discussion.

A particular focus in 2019 will be the relation of glucose control mechanisms with mitochondrial biology, linking the proximal steps in glucose metabolism with terminal catabolic processes. The meeting will also include sessions on tissue-specific control mechanisms (e.g. adipose, liver, heart). A new session on genetic diversity and sex in the modulation of glucose homeostasis will feature scientists that lead this field as well as younger faculty in the early stages of their independent careers. We believe the meeting themes are particularly well-aligned with challenges faced by the pharmaceutical and biotech industries in identifying new and tractable therapeutic approaches to combat a broad swath of metabolic disorders.

Conference sessions will present the latest research findings in eight interactive sessions:

  • Crossing the Divide: Glucose Transport Into Cells and Tissues
  • Should I Stay or Should I Go Now? Signaling Pathways Modulating Nutrient Homeostasis
  • Where Did You Go? Tracking Glucose Utilization
  • Burn, Baby, Burn: Mitochondrial Glucose Metabolism
  • Fat Camp: Adipose Tissue as a Central Modulator of Glucose Utilization
  • Diversity Affairs: Impact of Genetic Diversity and Sex on Integrative Metabolism and Diabetes Risk
  • When a Cell Looks in the Mirror, Does it Think it’s Fat? Nutrient Sensing and Signaling
  • Resistance Report: Mechanisms of Insulin Resistance

In addition to the opening Keynote from Ann Louise Olson, PhD (University of Oklahoma Health Sciences Center) and our eight interactive oral sessions, we will conduct “scientist speed dating” to facilitate introductions, and “open mike night” allowing researchers to present hot new findings, two poster sessions, and a career development workshop on work-life balance.

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    Funding for this conference was made possible (in part) by 1 R13 DK 121501 -01 from NIDDK. The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention by trade names, commercial practices, or organizations imply endorsement by the U.S. Government.



    Conference Location

    Omni Rancho Las Palmas Resort
    41000 Bob Hope Drive
    Rancho Mirage, CA 92270 USA

    Conference Organizers

    Scott Summers, PhD
    Chair, Department of Nutrition and Integrative Physiology, and Co-Director, Diabetes and Metabolism Research Center, University of Utah, Salt Lake City, USA
    Deborah Muoio, PhD
    Professor of Medicine, Duke University, and Director of Basic Science Research, Sarah W. Stedman Nutrition and Metabolism Center, Duke Molecular Physiology Institute, Durham, NC, USA

    Keynote Speaker

    Ann Louise Olson, PhD
    University of Oklahoma Health Sciences Center