Conference Summary

This FASEB Science Research Conference (SRC) will be the second in a new series focused on IgE and Allergy. In 2016, we successfully launched the series with a celebration of the 50th year since the discovery of IgE. Although the pathologic role for IgE in allergy and asthma is now well established, the field recognizes that many outstanding questions remain to be answered. This scientific symposium focuses on the best and most current science regarding the structure, biogenesis, biologic characteristics, and degradation of IgE; IgE's roles in allergy and immunity; and the cell biology of mast cells and basophils. Other critical aspects of physiology and pathology related to allergic diseases will be featured, such as contributions by other immune effector cells, animal models, and translation from bench to the clinic.

The main objective of the conference is to bring together scientists from academic, industry, and clinical settings to focus on the latest developments in the field of IgE and allergy. The FASEB SRC infrastructure offers huge advantages and the Arizona location offers beautiful scenery, modern conference facilities, and easy access for air travel. From our experience, a gathering of 150-200 participants ensures a great deal of discussion and fosters collaborations among the attendees.

Themes of the conference include: 1) Immunoreceptors, Signal Transduction and Cell Biology of Mast Cells and Basophils; 2) Allergic Disease: Inflammation, Infection, Microbiota and Therapeutic Strategies; 3) Genetics and Regulation of TH2 responses, 4) B Cells and the Generation of IgE.

Conference session topics will include:

  • Viral infections, inflammation, and allergic diseases
  • Immunotherapy
  • Murine models
  • Immunoregulatory mechanisms, microbiome
  • State-of-the-art imaging of single molecules, single cells, and tissues
  • Genetic polymorphisms, gene regulation in allergic diseases
  • Cell biology of receptor endocytosis, degranulation
  • Structure-function relationships in control of allergic reactions
  • Signaling molecules as therapeutic targets

In addition to an opening keynote lecture from Stephen Galli, PhD (Stanford University), this conference will feature 10 oral sessions, two poster sessions, lightning talks, and a career development workshop.

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    Funding for this conference was made possible [in part] by 1 R13 AI144965-01 from the National Institute of Allergy and Infectious Diseases. The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.


    Conference Location

    The Scottsdale Plaza Resort
    7200 N. Scottsdale Road
    Scottsdale, AZ 85253, USA

    Conference Organizers

    Ulrich Blank, PhD
    Research Director, Center of Research on Inflammation, French Institute of Health and Medical Research (INSERM), Paris

    Bridget Wilson, PhD
    Director, New Mexico Spatiotemporal Modeling Center, University of New Mexico, Albuquerque, USA

    John Ryan, PhD
    Associate Vice President for Research Development, Virginia Commonwealth University, Richmond, USA

    Keynote Speaker

    Stephen Galli, PhD
    Stanford University