Conference Summary

Since 2009, this bi-annual FASEB Science Research Conference (SRC) has alternated between the U.S. and Europe. It brings together experts from the fields of sirtuins, poly(ADP-ribose) polymerases (PARPs), calcium signaling, transcription, mitosis, immunology, and cancer with those specializing in drugs and nutritional interventions that interface with the fundamental and translational science of NAD+. It is the only scientific meeting that cuts across all these areas.

Understanding the whole NAD+ metabolome and NAD+-regulated proteome, as well as their regulatory mechanisms, is necessary to fully integrate individual research discoveries. This conference represents all major areas of NAD+ metabolism and signaling research, from molecular and chemical biology to specific areas of physiology and disease. It will promote the improvement of human health by investigating NAD+ metabolism and signaling in model organisms and humans. Finally, it will help train the next generation of investigators to advance NAD+ discovery sciences.

Themes of the conference include: 1) Explore the role of NAD+ in physiological aging, neurodegenerative diseases of aging, calcium signaling, and metabolic regulation; 2) Examine emerging research on NAD+ and its role in the biology of Sirtuins and PARPs in aging, inflammation, and metabolic regulation; 3) Explore the scope of NAD+ metabolites (NR and NMN) in the clinic.

Conference sessions will present the latest research findings and bring together groups of researchers who do not typically interact outside their respective sub-fields. New and exciting ideas are likely to emerge from such diverse, but ultimately unifying topics:

  • NAD+ in physiological aging and metabolic regulation
  • Sirtuins in aging and metabolic regulation
  • PARPs in aging, cancer, and metabolic regulation
  • NAD+ and neurodegenerative diseases of aging
  • NAD+-dependent calcium signaling in aging and metabolism
  • PARPs and NAD+ in inflammation related to cancer and disease
  • NAD+ metabolites (NR and NMN) in the clinic

The conference will feature 37 invited talks, 25 short talks selected from submitted abstracts, two poster sessions, and a "Meet the Experts Panel" hosted by the organizers, which will focus on career development and planning for the future of the field.

For consideration for a selected oral presentation, please submit your abstract by June 1, 2019.

Registration Prices

    Sign Up for Emails

    Funding for this conference was made possible, in part by R13AG063485-01A1 from National Institute on Aging (NIA) and the National Cancer Institute (NCI). ‘The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention by trade names, commercial practices, or organizations imply endorsement by the U.S. Government.



    Conference Location

    Trinity College Dublin
    College Green
    Dublin 2
    D02 PN40

    Conference Organizers

    Mathias Ziegler, MD, PhD
    Professor, Head of the Department of Biomedicine, University of Bergen, Norway

    W. Lee Kraus, PhD
    Professor, Obstetrics & Gynecology and Pharmacology and Director, Green Center for Reproductive Biology Sciences, University of Texas Southwestern Medical Center, Dallas, USA

    Danica Chen, PhD
    Associate Professor, Department of Nutritional Sciences & Toxicology, University of California, Berkeley, USA

    Marie Migaud, PhD
    Professor of Oncologic Sciences, Mitchell Cancer Institute, University of South Alabama, Mobile, USA

    Keynote Speaker

    Eric Verdin, PhD
    President and Chief Executive Officer, Buck Institute for Research on Aging

    Platinum Supporters