Conference Summary

Launched in 2007, this FASEB Science Research Conference (SRC) is the only scientific meeting of its kind dedicated to exploring protein acetylation from basic to clinical applications.

This conference will bring together a diverse group of scientists from academics and industry who study the biochemistry, structural biology, cellular mechanisms, physiology, and pharmacology of Lys acetylation functions and regulation.

Major themes of this conference are: 1) Explore the structure, functions, mechanisms, and regulation of HDACs, sirtuins, bromodomains, and Lys acetyltransferase; 2) Examine the dysregulation of protein acetylation and acylation in cancer, aging, and other diseases; 3) Develop novel chemical and pharmacological technologies applied to the study of protein acetylation.

Conference session topics will include:

  • Targeting acetylation in disease
  • Reversible acetylation and acylation in aging
  • Sirtuin regulation of deacetylation and deacylation in cancer and genomic stability
  • Chemical biology and small molecule modulators of protein acylation
  • Proteomics and enabling technologies for acylation
  • Epigenetics and chromatin signaling in aging and cancer
  • Structure of HATs and HDACs
  • Interplay of acetylation and metabolism in cancer and aging

In addition to an opening keynote lecture from Mitzi Kuroda, PhD (Harvard Medical School), this conference will feature 10 oral sessions, three poster sessions, and a career development session with academic, government, and industrial scientists discussing aspects of their jobs and successful strategies for obtaining positions. “Meet the Expert” lunch workshops will cover technologies including proteomics, chemical biology methods, structural studies using cryoEM, epigenetic techniques, and metabolomics.

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    Funding for this conference was made possible (in part) by 1R13CA239546-01 from the National Cancer Institute. The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the NIH; nor does mention by trade names, commercial practices, or organizations imply endorsement by the U.S. Government.  


    Conference Location

    Lisbon Marriott Hotel 
    Avenida dos Combatentes 45
    Lisboa (Lisbon)


    Conference Organizers

    Phil Cole, MD, PhD
    Professor, Medicine and Biological Chemistry and Molecular Pharmacology, Harvard Medical School and Brigham and Women's Hospital, Boston, MA, USA

    Katrin F. Chua, MD, PhD
    Associate Professor of Medicine, Stanford University, Director, Stanford MD-PhD program, and Investigator, VA Palo Alto Health Care System, Geriatric Research, Education, and Clinical Center, CA, USA

    Ileana Cristea, PhD
    Professor, Molecular Biology, Princeton University, NJ, USA

    Patrick Matthias, PhD
    Senior Group Leader, Friedrich Miescher Institute for Biomedical Research, and Adjunct Professor, Molecular Biology, University of Basel, Switzerland

    Keynote Speaker

    Mitzi Kuroda, PhD
    Harvard Medical School